A new study by researchers from the International Agency for Research on Cancer (IARC) and international partners determined the utility of detecting high-grade cervical intraepithelial neoplasia (CIN2+) lesions with endocervical involvement by using endocervical curettage and treating them with the loop electrosurgical excision procedure (LEEP) plus top hat excision among women with HIV. The results have been published in the International Journal of Gynecology & Obstetrics.
This cross‐sectional, prospective study was performed at the Coptic Hope Center for Infectious Diseases, an HIV treatment clinic in Nairobi, Kenya, between June 2011 and August 2016. More than 5000 participants were screened for the study.
The researchers found that among women with HIV, adding endocervical curettage did not increase detection of precancerous disease significantly, and treatment with LEEP plus top hat for CIN2+ lesions with endocervical involvement was comparable to treatment with LEEP for ectocervical CIN2+ lesions.
Chung MH, De Vuyst H, Greene SA, Topazian HM, Sayed S, Moloo Z, et al.
Loop electrosurgical excision procedure (LEEP) plus top hat for HIV-infected women with endocervical intraepithelial neoplasia in Kenya
Int J Gynecol Obstet, Published online 3 November 2020;