Publications

1. Alexandrov LB, Brennan P, Stratton MR (2026). Early-life mutagenesis and the rise of early-onset colorectal cancer. Cancer Discov. 16(4):644–6. https://doi.org/10.1158/2159-8290.CD-26-0166 PMID:41918355
2. Downham L, Laversanne M, Perdomo S, Filho AM, Bray F, Brennan P (2026). Increase of early-onset colorectal cancer: a cohort effect. J Natl Cancer Inst. 118(4):751–6. https://doi.org/10.1093/jnci/djaf238 PMID:40848248
3. Drevet G, Kalson L, Mangé L, Galateau-Salle F, Scherpereel A, Chalabreysse L, et al. (2026). Moving beyond morphology: toward a morpho-molecular classification of pleural mesothelioma. J Thorac Oncol. 21(5):103551. https://doi.org/10.1016/j.jtho.2026.01.003 PMID:41718511
4. Ecke TH, Collen S, Filicevas A, Yfantis T, Le Calvez-Kelm F, Jensen BT, et al. (2026). Urinary bladder cancer needs more attention – recommendations for health care professionals and politicians in the European Union. Nat Rev Urol. 23(1):40–9. https://doi.org/10.1038/s41585-025-01077-9 PMID:40830244
5. Laskar RS, Murphy N, Ferrari P, Brennan P, Cross AJ, Guevara M, et al. (2026). A prospective investigation of early-onset colorectal cancer risk factors – pooled analysis of three large-scale European cohorts. Br J Cancer. 134(5):781–9. https://doi.org/10.1038/s41416-025-03303-y PMID:41422343
6. Lopez-Bigas N, Kandyba E, Gonzalez-Perez A, Brennan P, Balmain A (2026). Tumour promotion through the lens of evolution. Nature. 652(8110):591–601. https://doi.org/10.1038/s41586-026-10386-x PMID:41986628
7. Pahnke S, Alcala K, Bulos Salim C, Cortez Cardoso Penha R, Park HA, Mckay J, et al. (2026). Lymphocyte count and risk of chronic lymphocytic leukemia. J Natl Cancer Inst. 118(4):636–42. https://doi.org/10.1093/jnci/djaf338 PMID:41324573
8. Perdomo S, de Carvalho AC, Ferreiro-Iglesias A, Ribeiro Pinto LF, Shibata T, Brennan P (2026). Mutational epidemiology: achievements and expectations on enhancing our understanding of the causes of cancer. J Natl Cancer Inst Monogr. 2026(72):15–22. https://doi.org/10.1093/jncimonographs/lgaf045 PMID:42008726
9. Zhang T, Zhao W, Wirth C, Díaz-Gay M, Yin J, Cecati M, et al. (2026). Uncovering the role of LINE-1 in the evolution of lung adenocarcinoma. Nature. 650(8100):230–41. https://doi.org/10.1038/s41586-025-09825-y PMID:41372401
10. Díaz-Gay M, Zhang T, Hoang PH, Leduc C, Baine MK, Travis WD, et al. (2025). The mutagenic forces shaping the genomes of lung cancer in never smokers. Nature. 644(8075):133–44. https://doi.org/10.1038/s41586-025-09219-0 PMID:40604281
11. Ebrahimi E, Naudin S, Dimou N, Mayén AL, Wang M, Abnet CC, et al. (2025). Alcohol consumption and upper aerodigestive tract squamous cell carcinoma: evidence from 28 prospective cohorts. J Natl Cancer Inst. 117(12):2598–611. https://doi.org/10.1093/jnci/djaf230 PMID:40977057
12. McElderry JP, Zhang T, Zhao W, Hoang PH, Anyaso-Samuel S, Sang J, et al. (2025). Microbiome analysis of 940 lung cancers in never-smokers reveals lack of clinically relevant associations. Nat Commun. 17(1):192. https://doi.org/10.1038/s41467-025-66780-y PMID:41387456
13. Naudin S, Wang M, Dimou N, Ebrahimi E, Genkinger J, Adami HO, et al. (2025). Alcohol intake and pancreatic cancer risk: an analysis from 30 prospective studies across Asia, Australia, Europe, and North America. PLoS Med. 22(5):e1004590. https://doi.org/10.1371/journal.pmed.1004590 PMID:40392909
14. Stratton MR, Humphreys L, Alexandrov LB, Balmain A, Brennan P, Campbell PJ, et al. (2025). Implementing mutational epidemiology on a global scale: lessons from Mutographs. Cancer Discov. 15(1):22–7. https://doi.org/10.1158/2159-8290.CD-24-1687 PMID:39801236
15. Díaz-Gay M, Dos Santos W, Moody S, Kazachkova M, Abbasi A, Steele CD, et al. (2025). Geographic and age variations in mutational processes in colorectal cancer. Nature. 643(8070):230–40. https://doi.org/10.1038/s41586-025-09025-8 PMID:40267983
16. Senkin S, Moody S, Díaz-Gay M, Abedi-Ardekani B, Cattiaux T, Ferreiro-Iglesias A, et al. (2024). Geographic variation of mutagenic exposures in kidney cancer genomes. Nature. 629(8013):910–8. https://doi.org/10.1038/s41586-024-07368-2 PMID:38693263
17. Ebrahimi E, Sangphukieo A, Park HA, Gaborieau V, Ferreiro-Iglesias A, Diergaarde B, et al.; HEADSpAcE Consortium (2025). Cross-ancestral GWAS identifies 29 variants across head and neck cancer subsites. Nat Commun. 16(1):8787. https://doi.org/10.1038/s41467-025-63842-z PMID:41038832
18. Torrens L, Moody S, de Carvalho AC, Kazachkova M, Abedi-Ardekani B, Cheema S, et al. (2025). The complexity of tobacco smoke-induced mutagenesis in head and neck cancer. Nat Genet. 57(4):884–96. https://doi.org/10.1038/s41588-025-02134-0 PMID:40164736
19. Perdomo S, Abedi-Ardekani B, de Carvalho AC, Ferreiro-Iglesias A, Gaborieau V, Cattiaux T, et al. (2024). The Mutographs biorepository: a unique genomic resource to study cancer around the world. Cell Genom. 4(3):100500. https://doi.org/10.1016/j.xgen.2024.100500 PMID:38325367
20. Purdue MP, Dutta D, Machiela MJ, Gorman BR, Winter T, Okuhara D, et al.; BioBank Japan Project; FinnGen (2024). Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions. Nat Genet. 56(5):809–18. https://doi.org/10.1038/s41588-024-01725-7 PMID:38671320