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Cancer, Public Health, and Society Teams
Cancer Inequalities Team (CIN)

Starting date: March 2021

Work Programme

Social inequalities in cancer incidence, survival, and mortality are large and affect all populations, although to a variable extent. The social gradient in cancer is characterized by complex patterns between and within countries, which are driven by a multifaceted and concurrent interplay of different factors.

The aim of the Cancer Inequalities Team (CIN) is to measure and monitor social inequalities in cancer and to compare them across populations and within the wider context of the global epidemiological transition of cancer, considering the inefficiencies in the provision of health-care services (e.g. overdiagnosis).

The programmatic areas of CIN are shown in the diagram.

CIN also aims to clarify the mechanisms (e.g. structural determinants of health) behind social inequalities in cancer, across all levels (e.g. individual and contextual, proximal and distal) and along the cancer continuum (e.g. risk factors, prevention, early detection, and treatment).

Cancer Inequalities

Team Composition

Team Leader: Dr Salvatore Vaccarella, Cancer Surveillance Branch (CSU), IARC
Email: VaccarellaS@iarc.who.int

Team members:
Dr Marzieh Eslahi (Postdoctoral Scientist, CSU)
Dr Maxime Large (Postdoctoral Scientist, CSU)
Dr Margherita Pizzato (Visiting Scientist, CSU)
Dr Sébastien Lamy (Visiting Scientist, CSU; INSERM, Toulouse, France)
Dr Valentina Lorenzoni (Visiting Scientist, CSU; Sant’Anna University, Pisa)
Mr Mohamed Youcef Ali (Master’s Student, CSU)
Dr Freddie Bray (Branch Head, CSU)
Dr Hadrien Charvat (Visiting Scientist, Scientific Consultant, CSU)

Key publications

  1. Vaccarella S, Georges D, Bray F, Ginsburg O, Charvat H, Martikainen P, et al. (2022). Socioeconomic inequalities in cancer mortality between and within countries in Europe: a population-based study. Lancet Reg Health Eur. 25:100551. https://doi.org/10.1016/j.lanepe.2022.100551 PMID:36818237
  2. Singh D, Vignat J, Lorenzoni V, Eslahi M, Ginsburg O, Lauby-Secretan B, et al. (2023). Global estimates of incidence and mortality of cervical cancer in 2020: a baseline analysis of the WHO Global Cervical Cancer Elimination Initiative. Lancet Glob Health. 11(2):e197–206. https://doi.org/10.1016/S2214-109X(22)00501-0 PMID:36528031
  3. Vaccarella S, Ginsburg O, Bray F (2021). Gender inequalities in cancer among young adults. Lancet Oncol. 22(2):166–7. https://doi.org/10.1016/S1470-2045(21)00001-2 PMID:33539738
  4. Li M, Zheng R, Dal Maso L, Zhang S, Wei W, Vaccarella S (2021). Mapping overdiagnosis of thyroid cancer in China. Lancet Diabetes Endocrinol. 9(6):330–2. https://doi.org/10.1016/S2213-8587(21)00083-8 PMID:33891886
  5. Lortet-Tieulent J, Georges D, Bray F, Vaccarella S (2020). Profiling global cancer incidence and mortality by socioeconomic development. Int J Cancer. 147(11):3029–36. https://doi.org/10.1002/ijc.33114 PMID:32449164
  6. Vaccarella S, Lortet-Tieulent J, Saracci R, Fidler MM, Conway DI, Vilahur N, et al. (2018). Reducing social inequalities in cancer: setting priorities for research. CA Cancer J Clin. 68(5):324–6. https://doi.org/10.3322/caac.21463 PMID:30152865
  7. Vaccarella S, Franceschi S, Zaridze D, Poljak M, Veerus P, Plummer M, et al. (2016). Preventable fractions of cervical cancer via effective screening in six Baltic, central, and eastern European countries 2017–40: a population-based study. Lancet Oncol. 17(10):1445–52. https://doi.org/10.1016/S1470-2045(16)30275-3 PMID:27567054
  8. Vaccarella S, Franceschi S, Bray F, Wild CP, Plummer M, Dal Maso L (2016). Worldwide thyroid-cancer epidemic? The increasing impact of overdiagnosis. N Engl J Med. 375(7):614–7. https://doi.org/10.1056/NEJMp1604412 PMID:27532827

    Landmark publication

    Vaccarella S, Lortet-Tieulent J, Saracci R, Conway DI, Straif K, Wild CP, editors (2019). Reducing social inequalities in cancer: evidence and priorities for research (IARC Scientific Publication No. 168). Lyon, France: International Agency for Research on Cancer. Available from: https://publications.iarc.who.int/580.




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