The International Agency for Research on Cancer (IARC) is pleased to announce that the IARC Monographs volume on night shift work is now available online.
This volume comprises a single monograph on night shift work. Night shift work was defined as work during the usual sleeping hours of the general population, and included transmeridian air travel. Disruption of normal physiological circadian rhythms is the most marked effect of night shift work. In health-care, manufacturing, transport, retail, and services sectors, night shift work is essential for ensuring that production and activities can continue 24 hours per day, 7 days per week. The IARC Monographs Working Group classified night shift work as “probably carcinogenic to humans” (Group 2A), on the basis of limited evidence of cancer in humans (for cancers of the breast, prostate, colon, and rectum), sufficient evidence of cancer in experimental animals, and strong mechanistic evidence in experimental animals.