A new study led by scientists at the International Agency for Research on Cancer (IARC) shows that adherence to healthy lifestyle habits is strongly inversely related to the risk of developing pancreatic cancer. The study examined smoking history, alcohol intake, diet, obesity, and physical activity in relation to the risk of developing pancreatic cancer within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.
Population attributable fractions were estimated under the assumption that the observed associations were causal. The results indicated that 14% of pancreatic cancer cases could have been avoided by controlling obesity, limiting alcohol consumption, adopting a healthy diet, and increasing the level of physical activity, and up to 19% of cases could have been avoided if smoking cessation was also pursued.
Pancreatic cancer is commonly diagnosed at a late stage. It is a highly fatal cancer, and limited opportunities are currently available for early detection and effective treatment. The identification of modifiable risk factors offers important scientific evidence to support the role of adopting healthy lifestyle habits in preventing the development of this disease.
Naudin S, Viallon V, Hashim D, Freisling H, Jenab M, Weiderpass E, et al.
Healthy lifestyle and the risk of pancreatic cancer in the EPIC study
Eur J Epidemiol, Published online 28 September 2019;