Molecular Mechanisms and Biomarkers Group

Recent Publications

Olivier, M., Bouaoun, L., Villar, S., Robitaille, A., Cahais, V., Heguy, A., Byrnes, G., Le Calvez-Kelm, F., Torres-Mejia, G., Alvarado-Cabrero, I., Imani-Razavi, F. S., Ines Sanchez, G., Jaramillo, R., Porras, C., Rodriguez, A. C., Garmendia, M. L., Soto, J. L., Romieu, I., Porter, P., Guenthoer, J., & Rinaldi, S. (2019). Molecular features of premenopausal breast cancers in Latin American women: Pilot results from the PRECAMA study. PloS One, 14(1), e0210372. PMID:30653559

Zhivagui, M., Ng, A. W. T., Ardin, M., Churchwell, M. I., Pandey, M., Renard, C., Villar, S., Cahais, V., Robitaille, A., Bouaoun, L., Heguy, A., Guyton, K. Z., Stampfer, M. R., McKay, J., Hollstein, M., Olivier, M., Rozen, S. G., Beland, F. A., Korenjak, M., & Zavadil, J. (2019). Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans. Genome Research, 29(4), 521-531. PMID:30846532

Fortuno, C., James, P. A., Young, E. L., Feng, B., Olivier, M., Pesaran, T., Tavtigian, S. V., & Spurdle, A. B. (2018). Improved, ACMG-compliant, in silico prediction of pathogenicity for missense substitutions encoded by TP53 variants. Human Mutation, 39(8), 1061-1069. PMID:29775997

Romieu, I., Biessy, C., Carayol, M., His, M., Torres-Mejia, G., Angeles-Llerenas, A., Sanchez, G. I., Jaramillo, R., Navarro, E., Porras, C., Ocampo, R., Rodriguez, A. C., Garmendia, M. L., Bustamante, E., Olivier, M., Porter, P., & Rinaldi, S. (2018). Reproductive factors and molecular subtypes of breast cancer among premenopausal women in Latin America: the PRECAMA study. Scientific Reports, 8(1), 13109. PMID:30166604

Viarisio, D., Muller-Decker, K., Accardi, R., Robitaille, A., Durst, M., Beer, K., Jansen, L., Flechtenmacher, C., Bozza, M., Harbottle, R., Voegele, C., Ardin, M., Zavadil, J., Caldeira, S., Gissmann, L., & Tommasino, M. (2018). Beta HPV38 oncoproteins act with a hit-and-run mechanism in ultraviolet radiation-induced skin carcinogenesis in mice. PLoS Pathogens, 14(1), e1006783. PMID:29324843

Dutta, S., Robitaille, A., Olivier, M., Rollison, D. E., Tommasino, M., & Gheit, T. (2017). Genome Sequence of a Novel Human Gammapapillomavirus Isolated from Skin. Genome Announc, 5(23). PMID:28596396

Hollstein, M., Alexandrov, L. B., Wild, C. P., Ardin, M., & Zavadil, J. (2017). Base changes in tumour DNA have the power to reveal the causes and evolution of cancer. Oncogene, 36(2), 158-167. PMID:27270430

Huang, M. N., Yu, W., Teoh, W. W., Ardin, M., Jusakul, A., Ng, A. W. T., Boot, A., Abedi-Ardekani, B., Villar, S., Myint, S. S., Othman, R., Poon, S. L., Heguy, A., Olivier, M., Hollstein, M., Tan, P., Teh, B. T., Sabapathy, K., Zavadil, J., & Rozen, S. G. (2017). Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors. Genome Research, 27(9), 1475-1486. PMID:28739859

Huskova, H., Ardin, M., Weninger, A., Vargova, K., Barrin, S., Villar, S., Olivier, M., Stopka, T., Herceg, Z., Hollstein, M., Zavadil, J., & Korenjak, M. (2017). Modeling cancer driver events in vitro using barrier bypass-clonal expansion assays and massively parallel sequencing. Oncogene, 36(43), 6041-6048. PMID:28692054

Vojtechova, Z., Zavadil, J., Klozar, J., Grega, M., & Tachezy, R. (2017). Comparison of the miRNA expression profiles in fresh frozen and formalin-fixed paraffin-embedded tonsillar tumors. PloS One, 12(6), e0179645. PMID:28644855

Zhivagui, M., Korenjak, M., & Zavadil, J. (2017). Modelling Mutation Spectra of Human Carcinogens Using Experimental Systems. Basic & Clinical Pharmacology & Toxicology, 121 Suppl 3, 16-22. PMID:27754614

Ardin, M., Cahais, V., Castells, X., Bouaoun, L., Byrnes, G., Herceg, Z., Zavadil, J., & Olivier, M. (2016). MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes. BMC Bioinformatics, 17, 170. PMID:27091472