Hepatocellular Carcinoma Displays Distinct DNA Methylation Signatures with Potential as Clinical Predictors
Hernandez-Vargas H,Lambert M-P,LeCalvez-Kelm F,Gouysse G,McKay-ChopinS,et al.
PLoSONE5(3):e9749.doi:10.1371/journal.pone.0009749
A wide panel of cancer-related genes was screened for aberrant epigenetic changes (DNA methylation) in liver cancer and premalignant (cirrhotic) liver lesions using Illumina bead array technology and DNA methylation signatures associated with major risk factors and clinical correlates were identified.Read article