DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility

A new study led by the International Agency for Research on Cancer (IARC) evaluates the link between the DNA methylation-based marker of ageing, known as the “epigenetic clock”, and breast cancer risk. The study, based on the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, a large prospective study conducted in 23 centres across 10 European countries, shows that an accelerated epigenetic clock is associated with susceptibility to postmenopausal breast cancer.

Ambatipudi S, Horvath S, Perrier F, Cuenin C, Hernandez-Vargas H, Le Calvez-Kelm F, et al.
DNA methylome analysis identifies accelerated epigenetic ageing associated with postmenopausal breast cancer susceptibility
Eur J Cancer, Published online 1 March 2017
http://dx.doi.org/10.1016/j.ejca.2017.01.014

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