Are two doses of human papillomavirus vaccine sufficient for girls aged 15–18 years? Results from a cohort study in India

New findings from a cohort study in India, published in the journal Papilloma Research, show that two doses of human papillomavirus (HPV) vaccine are as efficacious as three doses in girls aged 15–18 years. Earlier findings from this multicentre trial, which was initiated by the International Agency for Research on Cancer (IARC) in 2009, contributed to the World Health Organization (WHO) Strategic Advisory Group of Experts on Vaccination’s 2014 recommendation of a two-dose HPV vaccine schedule for adolescent girls aged less than 15 years. Based on the new findings, the current two-dose recommendation may be revised and extended to girls up to 18 years of age.

Bhatla N, Nene BM, Joshi S, Esmy PO, Poli URR, Joshi G, et al.
Are two doses of human papillomavirus vaccine sufficient for girls aged 15-18 years? Results from a cohort study in India.
Papillomavirus Res. 5:163–171;
http://dx.doi.org/10.1016/j.pvr.2018.03.008

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