A Low-dose ionizing diagnostic radiation to the chest at young age may increase risk of breast cancer in BRCA1/2 mutation carriers

The Gene-Rad-Risk study reports that ionizing radiation delivered in the course of diagnostic procedures to the chest before age 30 may increase breast cancer risk in women who carry a mutation in the BRCA1 or BRCA2 gene. The findings of the study, coordinated by the International Agency for Research on Cancer in Lyon, France, were published today online in the British Medical Journal.

Diagnostic radiation exposure and breast cancer risk among 1,993 BRCA1/2 mutation carriers: a retrospective cohort study (GENE-RAD-RISK).
A Pijpe, N Andrieu, DF Easton, A Kesminiene, E Cardis, et al.
BMJ 2012; 345 doi: 10.1136/bmj.e5660 (Published 6 September 2012

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