Targeted sequencing of circulating cell-free DNA (cfDNA) of Esophageal squamous cell carcinoma (ESCC) cases in the Golestan Cohort Study (GCS)
PI; Co-investigators from IARC: Dariush Nesheli, James McKay, Florence le Calvez-Kelm, Paul Brennan. Co-investigators from DDRI: Reza Malekzadeh

Mutographs of cancer: discovering the causes of cancer through mutational signatures.
Co-investigator; IARC PI: Paul Brennan; Sanger PI: Mike Startton. Plus multidisciplinary research team from GEP group.

Genetic and molecular characterization of bronchopulmonary carcinoids
Co-investigator. PI: Lynnette Fernandez-Cuesta at GCS group

Genomic analysis of inherited lung cancer: GeniLuc
Co-investigator; PI: James McKay, head of GCS group

ESCCAPE (Esophageal squamous cell carcinoma African prevention efforts)
Contributing; PI: Valerie McCormack at ENV section, Juachim Scholz, and multiple local PI from East Africa


Anantharaman D, Abedi-Ardekani B, Beachler DC, Gheit T, Olshan AF, Wisniewski K, Wunsch-Filho V, Toporcov TN, Tajara EH, Levi JE, Moyses RA, Boccia S, Cadoni G, Rindi G, Ahrens W, Merletti F, Conway DI, Wright S, Carreira C, Renard H, Chopard P, McKay-Chopin S, Scelo G, Tommasino M, Brennan P, D'Souza G. Geographic heterogeneity in the prevalence of human papillomavirus in head and neck cancer. Int J Cancer. 140(9):1968-1975. PMID:28108990. 2017

Scelo G, Riazalhosseini Y, Greger L, Letourneau L, Gonzàlez-Porta M, Wozniak MB, Bourgey M, Harnden P, Egevad L, Jackson SM, Karimzadeh M, Arseneault M, Lepage P, How-Kit A, Daunay A, Renault V, Blanché H, Tubacher E, Sehmoun J, Viksna J, Celms E, Opmanis M, Zarins A, Vasudev NS, Seywright M, Abedi-Ardekani B, Carreira C, Selby PJ, Cartledge JJ, Byrnes G, Zavadil J, Su J, Holcatova I, Brisuda A, Zaridze D, Moukeria A, Foretova L, Navratilova M, Mates D, Jinga V, Artemov A, Nedoluzhko A, Mazur A, Rastorguev S, Boulygina E, Heath S, Gut M, Bihoreau MT, Lechner D, Foglio M, Gut IG, Skryabin K, Prokhortchouk E, Cambon-Thomsen A, Rung J, Bourque G, Brennan P, Tost J, Banks RE, Brazma A, Lathrop GM. Variation in genomic landscape of clear cell renal cell carcinoma across Europe. Nat Commun. 5:5135.PMID:25351205. 2014

Abedi-Ardekani B, Dar NA, Mir MM, Zargar SA, Lone MM, Martel-Planche G, Villar S, Mounawar M, Saidi F, Malekzadeh R, Hainaut P. Epidermal growth factor receptor (EGFR) mutations and expression in squamous cell carcinoma of the esophagus in central Asia. BMC cancer. 12:602.PMID:23244191. 2012

Abedi-Ardekani B, Kamangar F, Sotoudeh M, Villar S, Islami F, Aghcheli K, Nasrollahzadeh D, Taghavi N, Dawsey SM, Abnet CC, Hewitt SM, Fahimi S, Saidi F, Brennan P, Boffetta P, Malekzadeh R, Hainaut P. Extremely high Tp53 mutation load in esophageal squamous cell carcinoma in Golestan Province, Iran. PLoS ONE. 6(12):e29488.PMID:22216294. 2011

Abedi-Ardekani B, Kamangar F, Hewitt SM, Hainaut P, Sotoudeh M, Abnet CC, Taylor PR, Boffetta P, Malekzadeh R, Dawsey SM. Polycyclic aromatic hydrocarbon exposure in oesophageal tissue and risk of oesophageal squamous cell carcinoma in north-eastern Iran. Gut. 59(9):1178-83. PMID:20584779. 2010


Member of the Iranian Society of Pathologists since 1998

Member of the Iranian Medical Council since 1994


Sep.1998: Second top graduate in Iranian Board of Pathology, Tehran (Iran) University of Medical sciences, Tehran, Iran
April 2007: Distinguished achievement award by Social security Organization for 9 years of valuable service in the field of medicine in Social Security Organization, Karaj, Iran
Feb. 2011: Distinguished published article in an international journal with high impact factor, (Abedi-Ardekani B, et al. Polycyclic aromatic hydrocarbon exposure in oesophageal tissue and risk of oesophageal squamous cell carcinoma in north-eastern Iran. Gut. 2010 Sep;59(9):1178-83;12th Avicenna Festival, Tehran university of Medical Sciences, Tehran, Iran