IARC researchers identify early blood protein markers of lung cancer that may improve early detection

Researchers from the International Agency for Research on Cancer (IARC) and partner institutions have identified protein markers in blood samples that are associated with future lung cancer diagnosis, and have developed an algorithm based on these markers to predict future lung cancer cases. These important complementary findings were published today as separate articles in Nature Communications and the Journal of the National Cancer Institute.

The Lung Cancer Cohort Consortium (LC3)
The blood proteome of imminent lung cancer diagnosis
Nat Commun, Published online 1 June 2023;
https://doi.org/10.1038/s41467-023-37979-8

Feng X, Wu WY, Onwuka JU, Haider Z, Alcala K, Smith-Byrne K, et al.
Lung cancer risk discrimination of pre-diagnostic proteomics measurements compared with existing prediction tools
J Natl Cancer Inst, Published online 1 June 2023;
https://doi.org/10.1093/jnci/djad071

Read IARC Press Release 337

Read the article in Nature Communications

Read the article in the Journal of the National Cancer Institute