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A new study led by researchers from the International Agency for Research on Cancer (IARC) assessed the presence of TP53 mutations in the cell-free DNA (cfDNA) extracted from the plasma of 51 small-cell lung cancer cases and 225 non-cancer controls. The detection of TP53 mutations in 11% of the controls poses serious challenges for the use of cfDNA in early detection of cancer.
Identification of circulating tumor DNA for the early detection of small-cell lung cancer
Fernandez-Cuesta L, Perdomo S, Avogbe PH, Leblay N, Delhomme TM, Gaborieau V, et al.
EBioMedicine. 2016; http://dx.doi.org/10.1016/j.ebiom.2016.06.032
Scientists from the International Agency for Research on Cancer (IARC) and partner institutions h...
La monographie sur l’aspartame, la première monographie du Volume 134 des Monographies du CIRC...
The International Agency for Research on Cancer (IARC) is pleased to announce the launch of the C...