Promising urine DNA test could facilitate detection of urothelial cancer

Scientists at the International Agency for Research on Cancer (IARC), in collaboration with researchers at the Protestant Clinic of Lyon (France), the Portuguese Oncology Institute of Porto (Portugal), and Lomonosov Moscow State University (Russian Federation), have developed a simple, sensitive, and specific urine test (called UroMuTERT) that is capable of detecting urothelial cancer (carcinoma of the bladder and of the upper urinary tract).

These exciting new results were published today in an article in EBioMedicine, a journal published by The Lancet. The new test could profoundly change the way in which urothelial cancer is detected and clinically managed.

Avogbe PH, Manel A, Vian E, Durand G, Forey N, Voegele C, et al.
Urinary TERT promoter mutations as non-invasive biomarkers for the comprehensive detection of urothelial cancer
EBioMedicine, Published online 20 May 2019;
https://doi.org/10.1016/j.ebiom.2019.05.004

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