New Release of the IARC TP53 Database

The Molecular Mechanisms and Biomarkers Group is pleased to announce the release of a new version of the IARC TP53 Database.

The IARC TP53 Database compiles TP53 gene variations identified in human populations and tumour samples, with associated data on tumour pathology and patient characteristics. The following molecular epidemiology data sets are available:

-TP53 somatic mutations in sporadic cancers
-TP53 germline mutations in familial cancers
-Common TP53 polymorphisms identified in human populations
-Functional and structural properties of p53 mutant proteins
-TP53 gene status in human cell lines
-Mouse models with engineered TP53.

This new release, R16 (November 2012), features an updated database that can be searched and analysed with new interactive tools through a redesigned web interface.Read more