A rare truncating BRCA2 variant and genetic susceptibility to upper aerodigestive tract cancer

An international collaborative study led by researchers in the Genetic Cancer Susceptibility Group of the International Agency for Research on Cancer (IARC) links a genetic variant (rs11571833, K3326X) with susceptibility to upper aerodigestive tract cancers. The results have now been published in the Journal of the National Cancer Institute.

A rare truncating BRCA2 variant and genetic susceptibility to upper aerodigestive tract cancer
Manon Delahaye-Sourdeix, Devasena Anantharaman, Maria N. Timofeeva, Valerie Gaborieau, Amelie Chabrier, Maxime P. Vallee, et al.
JNCI J Natl Cancer Inst 2015, 107(5):djv037
doi: 10.1093/jnci/djv037
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